POSOLOGY (Greek ' Posos -HOW MUCH and logos -SCIENCE') is the science of doses .Since the optimum dose of drug to produce the desired therapeutic effect varies from person to person,therefore the doses of drug are actually expressed in the form of range.The prescribed dose is that which exert the Therapeutic effect in the majority of subject.It should be minimum for eliciting the desired therapeutic response and maximum that can be tolerated by an average subject.